Evidence for Maternal-Fetal Genotype Incompatibility as a Risk Factor for Schizophrenia
نویسندگان
چکیده
منابع مشابه
Evidence for Maternal-Fetal Genotype Incompatibility as a Risk Factor for Schizophrenia
Prenatal/obstetric complications are implicated in schizophrenia susceptibility. Some complications may arise from maternal-fetal genotype incompatibility, a term used to describe maternal-fetal genotype combinations that produce an adverse prenatal environment. A review of maternal-fetal genotype incompatibility studies suggests that schizophrenia susceptibility is increased by maternal-fetal ...
متن کاملHLA-B maternal-fetal genotype matching increases risk of schizophrenia.
Schizophrenia and human leukocyte antigen (HLA) matching between couples or between mothers and offspring have independently been associated with prenatal/obstetric complications, including preeclampsia and low birth weight. Here, we report the results of a family-based candidate-gene study that brings together these two disparate lines of research by assessing maternal-fetal genotype matching ...
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Disorder in re-methylation process of homocysteine to methionine due to mutation in betaine homocysteine methyltransferase enzyme (BHMT) coding gene, leads to decrease in S-adenosyl methionine (SAM) synthesis which takes part in DNA methylation as a methyl donor. As a result, it can promote hypo-methylation of DNA, chromosome instability, and chromosome missegregation, which in turn is one of t...
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1. Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan 48824 USA 2. Division of Biostatistics, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, 72202 USA 3. Department of Statistics and Probability, Michigan State University, East Lansing, Michigan 48824 USA 4. Department of Mathematical Science, Peking Universit...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2010
ISSN: 1110-7243,1110-7251
DOI: 10.1155/2010/576318